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Low-Molecular-Weight heparins and Heparinoids in Acute ischemic Stroke Stroke 31:1770-1778, Bath,P.M.W. et al, 2000 See this aricle in Pubmed Article Abstract Low-molecular-weight heparins and heparinoids (LMWHs) are superior to unfractionated heparin in the prevention and treatment of venous thromboembolism and acute coronary syndromes. We performed a systematic review of randomized controlled trials (RCTs) to examine the safety and efficacy of LMWH in acute ischemic stroke. LMWHs reduce venous thromboembolic events in patients with acute ischemic stroke and increase the risk of extracranial bleeding. A nonsignificant reduction in combined death and disability and nonsignificant increases in case fatality and symptomatic intracranial hemorrhage were also observed. On the basis of the current evidence, LMWH should not be used in the routine management of patients with ischemic stroke.

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(click to filter results - removes previous filter) anticoagulant,complications of anticoagulant,treatment in CVD cerebrovascular accident cerebrovascular accident,acute management of heparin,low-molecular-weight heparinoid,low molecular weight intracerebral hemorrhage treatment of neurologic disorder

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